Editions universitaires europeennes ( 20.04.2018 )
€ 46,90
In this book, we explore the potential applications of functionalized folic acid-polymer nanoparticles in gene and drug delivery. Folic acid-chitosan (carbohydrates) and folic acid-PAMAM (dendrimers) of different sizes were used to transport DNA, RNA and drugs in vitro. Thermodynamic analysis showed conjugation of DNA, RNA and drug to nanoparticles occurred via hydrophilic, hydrophobic, H-bonding and van der Waals contacts. Major alterations of DNA and RNA morphology occurred by nanocarrier interaction, while drugs induced polymer morphological changes. Functionalized folic acid-nanoparticles can deliver DNA, RNA and drugs to the target molecules.
Détails du livre: |
|
ISBN-13: |
978-620-2-28960-3 |
ISBN-10: |
6202289600 |
EAN: |
9786202289603 |
Langue du Livre: |
English |
de (auteur) : |
Heidar-Ali Tajmir-Riahi |
Nombre de pages: |
192 |
Publié le: |
20.04.2018 |
Catégorie: |
Médecine |